A Veritas Biotecnologia em parceria com a empresa norte americana Zymo Research (www.zymoresearch.com) oferece uma ampla gama de serviços especializados para genômica, metilação, chip-seq, RNA-seq, Microbiomics, Mass Spec e Epigenética. Consulte-nos sobre os prazos de execução, preços e bioinformática.
Comprehensive Suite of Genome-wide DNA Methylation Analysis Techniques
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Targeted Sequencing for DNA Methylation Analysis
Zymo Research makes epigenetic biomarker validation simple with our MethylCheck™ platform. Whether you have methylation array (27K/450K/850K) data that you would like to validate in a large sample cohort or a specific gene region in mind, our scientists are available to design, validate, and evaluate site-specific DNA methylation changes. Simply send us your samples and regions of interest, and we will perform every step through data analysis, sending you back publication-quality graphs and figures.
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ChIP-Seq Overview
ChIP-Seq is a powerful tool for genome-wide mapping of histone modifications, protein-DNA interactions, and identifying consensus protein-binding sites in DNA. With the ChIP-Seq service from Zymo Research, you can either perform the ChIP assay yourself and send us the enriched DNA for library construction and Next-Gen sequencing, or we can process your samples using our optimized, proprietary chromatin shearing and enrichment procedures. We also perform the bioinformatics and statistical analyses, and send you the results in publication-ready format.
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Gene Expression Analysis
Zymo Research's RNA-Seq service makes Next-Gen transcriptome analysis available to every researcher, without the need for expensive equipment or bioinformatics expertise. Now you can achieve transcriptome-wide coverage of total RNA or small RNA with the latest Next-Gen sequencing technology.
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Why consider a Next-Gen Sequencing approach to analyze microbial communities?
Because many microbes can't be cultured and are missed using conventional analysis techniques. Using Next-Gen Sequencing it is possible to accurately assess entire microbial communities (microbiomes) using targeted (16S rRNA gene) or whole genome sequencing without the need for culturing.
Molecular biology is currently being revolutionized by whole-genome sequencing of individual microorganisms, as well as entire microbial communities (microbiomes), a field known as metagenomics. With direct access to the genomes of microorganisms in their natural habitat, metagenomics has been applied in environmental studies as well as biomarker research and has opened a new era in the study of microbial diversity.
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Precise, Accurate Global 5-mC & 5-hmC Quantification
Zymo Research offers a service for global analysis of DNA methylation and DNA hydroxymethylation using a unique LC/MS (MRM) platform. This Mass Spec-based service allows very sensitive, accurate, and quantitative analysis of the levels of 5-methylcytosine (5-mC) and 5-hydroxymethylcytosine (5-hmC) modifications in DNA. Please inquire for more information.
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