First-void urine collection using Colli-Pee™

Traditionally, first-void urine or first-catch urine is collected by having the patient start to urinate into a specimen container, stop when the container is full, and then continue voiding into the toilet again. However, for men this can be a problem as they are not able to stop the urine flow, whereas women has difficulties in correctly positioning the container. Colli-Pee™ is a device especially designed for first-void urine collection by capturing the first 20ml of a urine sample more efficiently and requiring less effort from the user. Colli-Pee™ has a unique inherent float system, which prevents midstream urine from entering the specimen container after it has been filled with first-void urine, all the while creating a passage through which the superfluous urine can pass through the device into the toilet. With this device, the patient can collect a first-void urine sample without having to interrupt the urine flow. First-void urine can be used to detect e.g. Sexually Transmitted Infections, such as: Human Papilloma Virus (HPV)ChlamydiaGonorrheaMycoplasma GenitaliumTrichomonas

The importance of first-void urine

For the detection of Sexually Transmitted Infections (STIs), a first-void urine sample needs to be collected, as this fraction of the urine stream contains more DNA and RNA particles than other fractions and thereby improves the diagnostic sensitivity and specificity compared to midstream (Vorsters et al 2014). The Colli-Pee™ device efficiently captures first-void urine and makes sure that superfluous urine is not collected, but flows in the toiled instead. Colli-Pee™ is a user-friendly device and provides an efficient, non-invasive sampling method that can be performed by the patient itself at the comfort of its own home.

Benefits of self-sampling systems like Colli-Pee™

Self-sampling techniques can provide STI screening to a wider ranger of venues including low-income, high-risk and resource-poor communities, hence maximizing the programme coverage for the management of symptomatic and asymptomatic cases. This has been seen in various studies that have compared self-sampling tests to clinical tests in various communities, they conclude that self-sampling can lower threshold for sampling (Shih et al 2011).

"Women in the home testing group (60%) were more likely to self-collect a vaginal sample than women in the clinic testing group (42%, RR 1.4, 95% CI 1.2-1.7)"

"Home-based screening was up to 11 times greater than the testing rate with clinic-based screening. For most individuals, self-collection and testing of urine or vaginal specimens at home was considered to be easy, acceptable, and often preferred over testing at a clinic."

There is also evidence from various studies that suggest urine tests have a good accuracy for the detection of cervical HPV and that first-void is even more accurate than midstream urine. Colli-Pee™ is a good alternative to reach more people, while still guaranteeing analytical performance (see studies).

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